Francis Collins is stepping down as the head of the NHGRI. Sure, I don't agree with his take on religion, but Collins did a damn fine job of heading up the Human Genome Project, and then working his butt off in Washington to secure funding and political support for genomics projects. He's a major reason that the field has advanced so rapidly in recent years.
In addition to his bureaucratic duties, Collins' own lab does some pretty nice work related to genetic disease, including the very interesting syndrome known as progeria. He's also a great communicator, and if you ever get a chance to hear him speak, either on his own research or on genomics as a whole, don't miss it.